Publications
PRISM Research Highlights
Vaccine Effectiveness & Variants
British Medical Journal (BMJ)
March 9, 2022
Clinical Severity of, and Effectiveness of mRNA Vaccines Against, COVID-19 From Omicron, Delta, and Alpha SARS-CoV-2 Variants in the United States
Key Finding: Evaluated multi-variant mRNA vaccine protection against severe outcomes across nationwide medical centers.
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Critical Care & Intubation
Journal of the American Medical Association (JAMA)
July 19, 2022
Effect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation
Key Finding (PREPARE II Trial): Fluid bolus administration did not significantly decrease the incidence of cardiovascular collapse during intubation.
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COVID-19 Hospitalization
Journal of the American Medical Association (JAMA)
November 4, 2021
Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity
Key Finding: Vaccination significantly reduced risk of ICU admission and invasive mechanical ventilation among hospitalized adults.
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Sepsis & ICU Outcomes
Journal of the American Medical Association (JAMA)
February 23, 2021
Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients with Sepsis - The VICTAS Randomized Clinical Trial
Key Finding (VICTAS Trial): Treatment combination did not significantly increase ventilator- or vasopressor-free days in septic patients.
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Anticoagulation & Thrombosis
New England Journal of Medicine (NEJM)
August 26, 2021
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with COVID-19
Key Finding: Therapeutic anticoagulation did not increase survival to hospital discharge in critically ill ICU patients.
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All PRISM Publications
American Journal of Cardiology
September 15, 2022
Risk of Cardiovascular Events After COVID-19
Read the article here ↗
Influenza and Other Respiratory Viruses
July 2022
Associations Between Persistent Symptoms After Mild COVID-19 and Long-Term Health Status, Quality of Life, and Psychological Distress
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Journal of the American Medical Association (JAMA)
June 16, 2022
Effect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation
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Medicina (Lithuania)
June 2, 2022
Ventricular Arrhythmias in Patients with Implanted Cardiac Devices at High Risk of Obstructive Sleep Apnea
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Pulmonary Circulation
April 2022
Echocardiographic Characteristics of Patients with Antisynthetase Syndrome
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Journal of Clinical and Translational Science
April 25, 2022
Modeling Clinical Trajectory Status of Critically Ill COVID-19 Patients Over Time
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Morbidity and Mortality Weekly Report (MMWR)
March 25, 2022
Effectiveness of mRNA Vaccination in Preventing COVID-19-Associated Invasive Mechanical Ventilation and Death - United States, March 2021 - January 2022
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British Medical Journal (BMJ)
March 9, 2022
Clinical Severity of, and Effectiveness of mRNA Vaccines Against, COVID-19 From Omicron, Delta, and Alpha SARS-CoV-2 Variants in the United States
Read the article here ↗
The Lancet Respiratory Medicine
February 3, 2022
Efficacy and Safety of Baricitinib Plus Standard of Care for the Treatment of Critically Ill Hospitalised Adults with COVID-19 on Invasive Mechanical Ventilation or Extracorporeal Membrane Oxygenation
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Chest
January 30, 2022
Organization of Outpatient Care After COVID-19 Hospitalization
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Morbidity and Mortality Weekly Report (MMWR)
January 28, 2022
Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization Among Immunocompetent and Immunocompromised Adults - United States, August - December 2021
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Chest
2021
Effect of Early High-Dose Vitamin D3 Repletion on Cognitive Outcomes in Critically Ill Adults
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Journal of Infectious Diseases
December 21, 2021
Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March - August 2021
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Journal of the American Medical Association (JAMA)
November 4, 2021
Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity
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Morbidity and Mortality Weekly Report (MMWR)
September 24, 2021
Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions - United States, March - August 2021
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The Lancet Respiratory Medicine
September 1, 2021
Efficacy and Safety of Baricitinib for the Treatment of Hospitalized Adults with COVID-19 (COV-BARRIER)
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Vaccine
August 7, 2021
Influenza Vaccine Acceptance and Hesitancy Among Adults Hospitalized with Severe Acute Respiratory Illnesses, United States 2019 - 2020
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Clinical Infectious Diseases
August 6, 2021
Effectiveness of Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccines for Preventing Coronavirus Disease 2019 Hospitalizations in the United States
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New England Journal of Medicine (NEJM)
August 4, 2021
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with COVID-19
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Clinical Infectious Diseases
May 20, 2021
Influenza Vaccine Effectiveness for Prevention of Severe Influenza-Associated Illness Among Adults in the United States, 2019 - 2020
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Journal of Infectious Diseases
May 20, 2021
Modeling the Impacts of Clinical Influenza Testing on Influenza Vaccine Effectiveness Estimates
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Clinical Infectious Diseases
May 12, 2021
Adults Hospitalized with Coronavirus Disease 2019 (COVID-19) - United States, March - June and October - December 2020
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Morbidity and Mortality Weekly Report (MMWR)
May 7, 2021
Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years - United States, January - March 2021
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Chest
April 6, 2021
A 44-Year-Old Man Presenting with Massive Hemoptysis and Dyspnea
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Journal of the American Medical Association (JAMA)
February 23, 2021
Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients with Sepsis - The VICTAS Randomized Clinical Trial
Read the article here ↗
Antimicrobial Agents and Chemotherapy
January 20, 2021
Pharmacokinetic and Pharmacodynamic Profiling of Minocycline for Injection Following a Single Infusion in Critically Ill Adults in a Phase IV Open-Label Multicenter Study (Acumin)
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Echocardiography
January 11, 2021
Inferior Vena Cava Dilation Predicts Global Cardiac Dysfunction in Acute Respiratory Distress Syndrome
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Clinical Infectious Diseases
September 25, 2020
Incorporating Real-Time Influenza Detection into the Test-Negative Design for Estimating Influenza Vaccine Effectiveness
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Read all of Dr. Khan’s publications here: