TESICO

A Multicenter, Adaptative, Randomized, Blinded Controlled Trial of the Safety and Efficacy of investigational Therapeutics for Hospitalized Patients with Acute Respiratory Distress Syndrome associated with COVID-19. (TESICO)

TESICO is a master protocol to evaluate the safety and efficacy of investigational agents aimed at improving outcomes for patients with acute respiratory failure related to COVID-19. The focus in this master protocol is on patients with critical respiratory failure (i.e., those receiving high-flow nasal cannula, non-invasive ventilation, invasive mechanical ventilation or ECMO to treat acute hypoxemic respiratory failure caused by SARS-CoV-2 pneumonia).